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CAS No. | 890819-86-0 | Cat. No. | BCP37902 |
Name | ML349 | ||
Synonyms | ML-349; ML 349; | ||
SMILES | COC1=CC=C(C=C1)N2CCN(CC2)C(=O)C3=CC4=C(S3)C5=CC=CC=C5S(=O)(=O)C4 | ||
Chemical Name | |||
Formula | C23H22N2O4S2 | M. Wt | 454.56 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ML 349 is a potent, specific acyl protein thioesterase 2 (APT-2, LYPLA2) inhibitor with IC50 of 144 nM and Ki of 120 nM, >20-fold selectivity over APT-1 and serine hydrolase enzyme family. |
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