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CAS No. | 924296-19-5 | Cat. No. | BCP46476 |
Name | DUBs-IN-2 | ||
Synonyms | DUB-IN-2; | ||
SMILES | CCON=C1C2=CC=CC=C2C3=NC(=C(N=C31)C#N)C#N | ||
Chemical Name | |||
Formula | C15H9N5O | M. Wt | 275.26 |
Purity | 98% | Storage | Store at 4-8°C |
Description | DUBs-IN-2 is a potent deubiquitinase inhibitor with an IC50 of 0.28 μM for USP8.In Vitro:DUBs-IN-2 is a potent USP8 inhibitor with an IC50 of 0.28 μM, and has no effect on USP7, with an IC50 of >100 μM. DUBs-IN-2 inhibits the viability of HCT116 colon cell line and PC-3 prostate cancer cell line with IC50 values of 0.5-1.5 μM. |
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