LCQ-908 New
Data Sheet
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| CAS No. | 956136-95-1 | Cat. No. | BCP21089 |
| Name | LCQ-908 | ||
| Synonyms | LCQ908; LCQ 908; Pradigastat; | ||
| SMILES | C1CC(CCC1CC(=O)O)C2=CC=C(C=C2)C3=NC=C(C=C3)NC4=CN=C(C=C4)C(F)(F)F | ||
| Chemical Name | |||
| Formula | C25H24F3N3O2 | M. Wt | 455.48 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Pradigastat, also known as LCQ-908, is potent and oral DGAT1 inhibitor. Pradigastat is being developed for the treatment of familial chylomicronemia syndrome. Familial chylomicronemia syndrome (FCS) is a rare lipid disease caused by complete lipoprotein lipase (LPL) deficiency resulting in fasting chylomicronemia and severe hypertriglyceridemia. Inhibition of diacylglycerol acyltransferase 1 (DGAT1), which mediates chylomicron triglyceride (TG) synthesis, is an attractive strategy to reduce TG levels in FCS . | ||
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