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Mitochondrial Metabolism

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Mitochondrial Metabolism

Chemical Structure Cat. No. Product Name CAS No.
Ninerafaxstat 3HCl Chemical Structure
 BCP49659 Ninerafaxstat 3HCl 2311824-72-1
Ninerafaxstat trihydrochloride shifts cellular metabolism to glucose oxidation from fatty acid oxidation. Ninerafaxstat trihydrochloride improves overall mitochondrial respiration and reduces fatty acid oxidation, thereby inhibiting the proliferation and growth of cancer cells.
ZK53 Chemical Structure
 BCP49658 ZK53 3031789-26-8
ZK53 is a selective and potent activator of mitochondrial casein hydrolase protease P (HsClpP).ZK53 induces apoptosis and inhibits the hydrolysis of alpha-casein by HsClpP.ZK53 inhibits tumour growth in xenografts and native mouse models.
BAY-179 Chemical Structure
 BCP49597 BAY-179 2764880-87-5
BAY-179 is a potent, selective, and species cross-reactive OXPHOS complex I inhibitor.
Mitochondrial fusion promoter M1 Chemical Structure
 BCP48945 Mitochondrial fusion promoter M1 219315-22-7
Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator that increases the expression of mitofusin 2, a mitochondrial outer membrane fusion protein, reduces brain mitochondrial dysfunction.
DX3-213B Chemical Structure
 BCP46463 DX3-213B 2749555-66-4
DX3-213B is a highly potent, orally active oxidative phosphorylation (OXPHOS) complex I inhibitor. DX3-213B impairs ATP generation, and blocks MIA PaCa-2 cell growth.
Mito-apocynin (C11) Chemical Structure
 BCP46038 Mito-apocynin (C11) 1254044-38-6
Mito-apocynin (C11), an orally active mitochondria-targeted triphenylphosphonium (TPP)-based compound, is synthesized by conjugating the Apocynin moiety with a TPP+ cation.
L-Histidine Chemical Structure
 BCP45568 L-Histidine 71-00-1
L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
NL-1 Chemical Structure
 BCP45211 NL-1 188532-26-5
NL-1 is a mitoNEET inhibitor with antileukemic effect.
MitoTEMPO Chemical Structure
 BCP43473 MitoTEMPO 1334850-99-5
Mito-TEMPO is a mitochondria-targeted superoxide dismutase mimetic with superoxide and alkyl radical scavenging properties.
Mito-LND Chemical Structure
 BCP42814 Mito-LND 2361564-49-8
Mito-LND is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation (OXPHOS).
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