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GSK215 Chemical Structure

GSK215

Data Sheet For research use only. Not for human use.
Cat. No. :BCP46447CAS No. :2743427-26-9Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2743427-26-9 Cat. No. BCP46447
Name GSK215
Synonyms GSK-215;GSK 215;
SMILES
Chemical Name
Formula C50H59F3N10O6S M. Wt 985.14
Purity 98% Storage Store at 4-8°C
Description GSK215 is a potent and selective PROTAC focal adhesion kinase (FAK) degrader. GSK215 is designed by a binder for the VHL E3 ligase and the FAK inhibitor VS-4718. GSK215 induces rapid and prolonged FAK degradation, giving a long-lasting effect on FAK levels and a marked pharmacokinetic/pharmacodynamics (PK/PD) disconnect.
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