PF-562271 benzenesulfonate
Data Sheet
For research use only. Not for human use.
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| CAS No. | 939791-38-5 | Cat. No. | BCP14770 |
| Related Products | 717907-75-0（PF562271） 939791-41-0（PF-562271 Hydrochloride） | ||
| Name | PF-562271 benzenesulfonate | ||
| Synonyms | PF562271; PF562271; PF-562271; PF-00562271; PF00562271; PF 00562271;PF562271 benzesulfonate salt;; PF562271 besylate; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C21H20F3N7O3S.C6H6O3S | M. Wt | 665.67 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | PF-562271 (besylate) is a potent, ATP-competitive, reversible inhibitor of FAK and Pyk2 kinase with IC50 of 1.5 nM and 13 nM, and has > 100-fold selectivity against other protein kinases, except for some CDKs.PF-562271, also known as PF-562,271, is an orally bioavailable small molecule and ATP-competitive focal adhesion kinase (FAK) inhibitor with potential antineoplastic and antiangiogenic activities. PF-562271 inhibits the tyrosine kinase FAK, and to a lesser extent, proline-rich tyrosine kinase (PYK2), which may inhibit tumor cell migration, proliferation, and survival. Note: PF-562271 benzesulfonate is also called PF-562271 besylate. | ||
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