Cl-amidine TFA New
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CAS No. | 1043444-18-3 | Cat. No. | BCP43968 |
Name | Cl-amidine TFA | ||
Synonyms | Cl-Amidine (trifluoroacetate salt);Cl-amidine TFA; | ||
SMILES | C1=CC=C(C=C1)C(=O)NC(CCCN=C(CCl)N)C(=O)N.C(=O)(C(F)(F)F)O | ||
Chemical Name | |||
Formula | C14H19ClN4O2.C2HF3O2 | M. Wt | 424.81 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Cl-amidine is an inhibitor of irreversible protein pan-peptidylarginine deiminase (PAD) with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. It irreversibly inactivates all four PAD subtypes by covalently modifying an active site cysteine that is important for its catalytic activity. |
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