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Cl-amidine TFA Chemical Structure

Cl-amidine TFA

Data Sheet For research use only. Not for human use.
Cat. No. :BCP43968CAS No. :1043444-18-3Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 1043444-18-3 Cat. No. BCP43968
Name Cl-amidine TFA
Synonyms Cl-Amidine (trifluoroacetate salt);Cl-amidine TFA;
SMILES C1=CC=C(C=C1)C(=O)NC(CCCN=C(CCl)N)C(=O)N.C(=O)(C(F)(F)F)O
Chemical Name
Formula C14H19ClN4O2.C2HF3O2 M. Wt 424.81
Purity 98% Storage Store at 4-8°C
Description Cl-amidine is an inhibitor of irreversible protein pan-peptidylarginine deiminase (PAD) with IC50 values of 5.9 ± 0.3 μM, 0.8 ± 0.3 μM, 6.2 ± 1.0 μM for PAD4, PAD1 and PAD3, respectively. It irreversibly inactivates all four PAD subtypes by covalently modifying an active site cysteine that is important for its catalytic activity.
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