BB-Cl-Amidine hydrochloride New
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | BB-Cl-AmidineHCl | Cat. No. | BCP36632 |
| Name | BB-Cl-Amidine hydrochloride | ||
| Synonyms | BB-Cl-Amidine HCl; | ||
| SMILES | C1=CC=C(C=C1)C2=CC=C(C=C2)C(=O)NC(CCCN=C(CCl)N)C3=NC4=CC=CC=C4N3.Cl | ||
| Chemical Name | |||
| Formula | C26H27Cl2N5O | M. Wt | 496.43 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | BB-Cl-Amidine hydrochloride is a peptidylarginine deminase (PAD) inhibitor.BB-Cl-Amidine is a Novel Therapeutic for Canine and Feline Mammary Cancer via Activation of the Endoplasmic Reticulum Stress Pathway. BB-Cl-Amidine is a modified version of Cl-amidine that retains the functional components but possesses a C-terminal benzimidazole group designed to limit proteolysis of the C-terminal amide. BB-CLA reduced viability and tumorigenicity of canine and feline mammary cancer cell lines in vitro. BB-CLA activates the endoplasmic reticulum stress pathway in these cells by downregulating 78 kDa Glucose-regulated Protein (GRP78), a potential target in breast cancer for molecular therapy, and upregulating the downstream target gene DNA Damage Inducible Transcript 3 (DDIT3). | ||
Recommend Products
More >
-
BMS-P5 hydrochloride
Cat. No.：BCP44953
No.：1549811-36-0
Product Details -
Cl-amidine TFA
Cat. No.：BCP43968
No.：1043444-18-3
Product Details -
GSK106 hydrochloride
Cat. No.：BCP37874
No.：1652591-82-6
Product Details -
GSK121 trifluoroacetate salt
Cat. No.：BCP37872
No.：1652591-80-4
Product Details -
-
GSK199 hydrochloride
Cat. No.：BCP30343
No.：1549811-53-1
Product Details -
BB-Cl-Amidine
Cat. No.：BCP30300
No.：1802637-39-3
Product Details -
-
GSK484 hydrochloride
Cat. No.：BCP25415
No.：1652591-81-5
Product Details -
Cl-Amidine
Cat. No.：BCP20202
No.：913723-61-2
Product Details
Tags:BB-Cl-Amidine hydrochloride supplier,BB-Cl-Amidine hydrochloride purchase,BB-Cl-Amidine hydrochloride manufacturer,BB-Cl-Amidine hydrochloride distributor,BB-Cl-Amidine hydrochloride cost,BB-Cl-Amidine hydrochloride buy,BB-Cl-Amidine hydrochloride for sale