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Hydrocortisone sodium succinate Chemical Structure

Hydrocortisone sodium succinate

Data Sheet For research use only. Not for human use.
Cat. No. :BCP38923CAS No. :125-04-2Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 125-04-2 Cat. No. BCP38923
Name Hydrocortisone sodium succinate
Synonyms Hydrocortisone 21-hemisuccinate sodium salt;
SMILES CC12CCC(=O)C=C1CCC3C2C(CC4(C3CCC4(C(=O)COC(=O)CCC(=O)[O-])O)C)O.[Na+]
Chemical Name
Formula C25H33NaO8 M. Wt 484.52
Purity 98% Storage Store at 4-8°C
Description Hydrocortisone Sodium Succinate is the sodium salt of hydrocortisone succinate with glucocorticoid property. Hydrocortisone sodium succinate is chemically similar to the endogenous hormone that stimulates anti-inflammatory and immunosuppressive activities, in addition to exhibiting minor mineralocorticoid effects. This agent binds to intracellular glucocorticoid receptors and is translocated into the nucleus, where it initiates the transcription of glucocorticoid-responsive genes, such as various cytokines and lipocortins. Lipocortins inhibit phospholipase A2, thereby blocking the release of arachidonic acid from membrane phospholipids and preventing the synthesis of prostaglandins and leukotrienes, both potent mediators of inflammation.
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