Mapracorat New
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| CAS No. | 887375-26-0 | Cat. No. | BCP32546 |
| Name | Mapracorat | ||
| Synonyms | ZK-245186; ZK 245186; ZK245186; BOL-303242; BOL303242; BOL 303242; BOL-303242-X; | ||
| SMILES | CC1=NC2=C(C=C1)C(=CC=C2)NCC(CC(C)(C)C3=CC(=CC4=C3OCC4)F)(C(F)(F)F)O | ||
| Chemical Name | |||
| Formula | C25H26F4N2O2 | M. Wt | 462.49 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Mapracorat is an selective glucocorticoid receptor agonists (SEGRAs) under clinical trials for the topical treatment of atopic dermatitis, inflammation following cataract surgery, and allergic conjunctivitis. Mapracorat inhibits hyperosmolar-induced cytokine release and MAPK pathways in human corneal epithelial cells. | ||
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