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CAS No. | 142645-19-0 | Cat. No. | BCP17018 |
Related Products | 1909226-00-1(BDA-366) 1821496-27-8(BDA 366) | ||
Name | BDA-366 | ||
Synonyms | BDA 366; BDA366;1909226-00-1; | ||
SMILES | CCN(CC)C[C@H](CNC1=C2C(=C(C=C1)NC[C@H]3CO3)C(=O)C4=CC=CC=C4C2=O)O | ||
Chemical Name | |||
Formula | C24H29N3O4 | M. Wt | 423.51 |
Purity | 98% | Storage | Store at 4-8°C |
Description | BDA-366 is a small-molecule Bcl2-BH4 domain antagonist, BDA-366, that binds BH4 with high affinity and selectivity. BDA-366-Bcl2 binding induces conformational change in Bcl2 that abrogates its antiapoptotic function, converting it from a survival molecule to a cell death inducer. |
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