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Ro 46-2005 Chemical Structure

Ro 46-2005

Data Sheet For research use only. Not for human use.
Cat. No. :BCP17756CAS No. :150725-87-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 150725-87-4 Cat. No. BCP17756
Name Ro 46-2005
Synonyms Ro 462005;Ro 46 2005;
SMILES
Chemical Name
Formula C23H27N3O6S M. Wt 473.54
Purity 98% Storage Store at 4-8°C
Description Ro 46-2005 proves to be equipotent (IC50 200-500 nM) for inhibition of [125I]ET-1 binding on the two known ET receptor subtypes (ETA and ETB). Ro 46-2005 also inhibits the functional consequences of ET-1 stimulation: the ET-l-induced release of arachidonic acid from rat mesangial cells was inhibited with an IC50 of 1.8 μM.
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