BQ-788 Sodium

Data Sheet For research use only. Not for human use.

Cat. No. ：BCP28133CAS No. ：156161-89-6Purity：98%

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Chemical Properties&Biological Activity

CAS No.	156161-89-6	Cat. No.	BCP28133
Name	BQ-788 Sodium
Synonyms	BQ-788 sodium salt ;BQ788; BQ-788; BQ 788;
SMILES
Chemical Name
Formula	C34H50N5O7.Na	M. Wt	663.79
Purity	98%	Storage	Store at 4-8°C
Description	BQ-788 (sodium salt) is a potent, selective ETB receptor antagonist with IC50 of 1.2 nM for inhibition of ET-1 binding to human Girardi heart cells, poorly inhibiting the binding to ETA receptors in human neuroblastoma cell line SK-N-MC cells with IC50 of 1300 nM.BQ788 is a endothelin B receptor antagonist. BQ788 attenuates stab wound injury-induced reactive astrocytes in rat brain. BQ788 were well tolerated and showed signs of directly and indirectly reducing the viability of melanoma cells.

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BQ-788 Sodium

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