Monastrol
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CAS No. | 329689-23-8 | Cat. No. | BCP06757 |
Name | Monastrol | ||
Synonyms | (±)-Monastrol; | ||
SMILES | |||
Chemical Name | |||
Formula | C14H16N2O3S | M. Wt | 292.35 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Monastrol is a kinesin Eg5 inhibitor. Induction of apoptosis by monastrol is independent of the spindle checkpoint. Monastrol binds to the KSP-ADP complex, forming a KSP-ADP- monastrol ternary complex, which cannot bind to microtubules productively and cannot undergo further ATP-driven conformational changes. |
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