Upadacitinib tartrate New
Data Sheet
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| CAS No. | 1607431-21-9 | Cat. No. | BCP19012 |
| Related Products | 2050057-56-0（Upadacitinib hemihydrate） 1310726-60-3（Upadacitinib） | ||
| Name | Upadacitinib tartrate | ||
| Synonyms | ABT-494 tartrate;ABT494 tartrate;ABT 494 tartrate; | ||
| SMILES | O=C(N1C[C@@H](CC)[C@@H](C2=CN=C3C=NC(NC=C4)=C4N32)C1)NCC(F)(F)F.O=C(O)[C@H](O)[C@@H](O)C(O)=O | ||
| Chemical Name | |||
| Formula | C21H25F3N6O7 | M. Wt | 530.46 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Upadacitinib, also known as ABT-494, is a potent and selective JAK inhibitors in development for rheumatoid arthritis. ABT-494 is approximately 74 fold selective for Jak1 over Jak2 in cellular assays dependent on specific, relevant cytokines. ABT-494 demonstrates efficacy in rat arthritis models. Preliminary evidence suggests that compared to tofacitinib, ABT-494 may spare Jak2 and Jak3 dependent signaling. | ||
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