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CAS No. | 882290-02-0 | Cat. No. | BCP46780 |
Name | SC99 | ||
Synonyms | SC-99; SC 99; | ||
SMILES | C1=CC(=CC=C1C(=O)C(=NNC2=CC(=C(C=C2)F)Cl)C#N)Cl | ||
Chemical Name | |||
Formula | C15H8Cl2FN3O | M. Wt | 336.15 |
Purity | 98% | Storage | Store at 4-8°C |
Description | SC99 is a selective inhibitor of JAK2-STAT3 activation. SC99 downregulates the expression of STAT3-modulated genes, including Bcl-2, Bcl-xL, VEGF, cyclin D2, and E2F-1. |
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