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CAS No. | 188532-26-5 | Cat. No. | BCP45211 |
Name | NL-1 | ||
Synonyms | NL1;NL 1; | ||
SMILES | CC(C)(C)C1=CC(=CC(=C1O)C(C)(C)C)CC2C(=O)NC(=O)S2 | ||
Chemical Name | |||
Formula | C18H25NO3S | M. Wt | 335.46 |
Purity | 98% | Storage | Store at 4-8°C |
Description | NL-1 is a mitoNEET inhibitor with antileukemic effect. NL-1 inhibits REH and REH/Ara-C cells growth with IC50s of 47.35 µM and 56.26 µM, respectively. NL-1-mediated death in leukemic cells requires the activation of the autophagic pathway. |
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