CCI-006 New
Data Sheet
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| CAS No. | 292053-42-0 | Cat. No. | BCP40217 |
| Name | CCI-006 | ||
| Synonyms | CCI006; CCI 006; | ||
| SMILES | COC(=O)C(=CC1=CC=C(O1)C2=CC=C(C=C2)S(=O)(=O)N)C#N | ||
| Chemical Name | Methyl (E)-2-cyano-3-[5-(4-sulfamoylphenyl)furan-2-yl]prop-2-enoate | ||
| Formula | C15H12N2O5S | M. Wt | 332.33 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | CCI-006 is a selective inhibitor and chemosensitizer of MLL-rearranged leukemia cells, by inhibiting mitochondrial respiration resulting in insurmountable mitochondrial depolarization and a pro-apoptotic unfolded protein response (UPR) in a subset of MLL-r leukemia cells. | ||
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