Bilastine Bulk
Data Sheet
For research use only. Not for human use.
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| CAS No. | 202189-78-4 | Cat. No. | BCP02576 |
| Name | Bilastine | ||
| Synonyms | Bilastinum;Ilaxten; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C28H37N3O3 | M. Wt | 463.61 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Bilastine binds to histamine H1-receptors as indicated by its displacement of [3H]-pyrilamine from H1-receptors expressed in guinea-pig cerebellum and human embryonic kidney (HEK) cell lines. The studies conducted on guinea-pig smooth muscle demonstrated the capability of bilastine to antagonise H1-receptors. Bilastine is selective for histamine H1-receptors as shown in receptor-binding screening conducted to determine the binding capacity of bilastine to 30 different receptors . Bilastine distribution has an apparent volume of distribution of 1.29 L/kg, and has an elimination half-life of 14.5 h and plasma protein binding of 84-90% . | ||
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