ASP2453 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2241719-73-1 | Cat. No. | BCP48490 |
| Name | ASP2453 | ||
| Synonyms | ASP 2453; ASP-2453; | ||
| SMILES | CC1=C(C2=C(C=C1)NN=C2)C3=C(C=C4C(=C3OCC(F)(F)F)N=C(N=C4N5CCC6(CC5)CN(C6)C(=O)C=C)OC7CCN(CC7)CCCOC)C8CC8 | ||
| Chemical Name | |||
| Formula | C40H48F3N7O4 | M. Wt | 747.85 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | ASP2453 is a potent, selective and covalent KRAS G12C inhibitor. ASP2453 inhibits the Son of Sevenless (SOS)-mediated interaction between KRAS G12C and Raf with an IC50 value of 40 nM. | ||
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