RM-018 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2641993-55-5 | Cat. No. | BCP48790 |
| Name | RM-018 | ||
| Synonyms | RM018;RM 018; | ||
| SMILES | CCN1C2=C3C=C(C=C2)C4=CC=CC(=C4)CC(C(=O)N5CCCC(N5)C(=O)OCC(CC3=C1C6=C(N=CC=C6)C(C)OC)(C)C)NC(=O)C(C(C)C)N(C)C(=O)C7CCN(C7)C(=O)C#CCN8CCOCC8 | ||
| Chemical Name | |||
| Formula | C56H72N8O8 | M. Wt | 985.24 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | RM-018 is a potent, functionally distinct tricomplex KRASG12C active-state inhibitor. RM-018 retains the ability to bind and inhibit KRASG12C/Y96D and could overcome resistance. RM-018 binds specifically to the GTP-bound, active [“RAS(ON)”] state of KRASG12C. | ||
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