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CAS No. | 2361241-23-6 | Cat. No. | BCP34713 |
Name | BI-749327 | ||
Synonyms | BI749327;BI 749327; | ||
SMILES | C1CN(CCC1C2=NN=C(C=C2)N)C(=O)C3=CC=C(C=C3)OC4=CC=C(C=C4)C(F)(F)F | ||
Chemical Name | |||
Formula | C23H21F3N4O2 | M. Wt | 442.43 |
Purity | 98% | Storage | Store at 4-8°C |
Description | BI-749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively. BI-749327 is 85-fold more selective for mouse TRPC6 than TRPC3 and 42-fold versus TRPC7. |
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