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BI-749327 Chemical Structure

BI-749327

Data Sheet For research use only. Not for human use.
Cat. No. :BCP34713CAS No. :2361241-23-6Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 2361241-23-6 Cat. No. BCP34713
Name BI-749327
Synonyms BI749327;BI 749327;
SMILES C1CN(CCC1C2=NN=C(C=C2)N)C(=O)C3=CC=C(C=C3)OC4=CC=C(C=C4)C(F)(F)F
Chemical Name
Formula C23H21F3N4O2 M. Wt 442.43
Purity 98% Storage Store at 4-8°C
Description BI-749327 is a potent, high selectivity and orally bioavailable TRPC6 antagonist, with IC50s of 13 nM, 19 nM and 15 nM for mouse, human and guinea pig TRPC6, respectively. BI-749327 is 85-fold more selective for mouse TRPC6 than TRPC3 and 42-fold versus TRPC7.
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