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CAS No. | 332382-54-4 | Cat. No. | BCP41268 |
Name | ML-SA1 | ||
Synonyms | Mucolipin synthetic agonist 1; | ||
SMILES | CC1CC(N(C2=CC=CC=C12)C(=O)CN3C(=O)C4=CC=CC=C4C3=O)(C)C | ||
Chemical Name | |||
Formula | C22H22N2O3 | M. Wt | 362.42 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ML-SA1 is an agonist of transient receptor potential mucolipin 1 (TRPML1). It induces cytosolic calcium increases and activates TRPML1-mediated current (IML1) in isolated vacuoles. It also activates whole-endolysosome IML1 in primary murine macrophages. |
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