RMC-5552 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2382768-62-7 | Cat. No. | BCP48880 |
| Name | RMC-5552 | ||
| Synonyms | RMC5552;RMC 5552; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C93H136N10O24 | M. Wt | 1778.16 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | RMC-5552 is a potent and selective mTORC1 inhibitor. RMC-5552 inhibits phosphorylation of mTORC1 pS6K and p4EBP1 with IC50s of 0.14 nM and 0.48 nM, respectively. RMC-5552 shows much lower pAKT inhibition (IC50 of 19 nM), resulting in mTORC1/mTORC2 selectivity approaching 40-fold. RMC-5552 has anti-cancer activity. | ||
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