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CAS No. | 406208-42-2 | Cat. No. | BCP41504 |
Name | ACHP | ||
Synonyms | 2-Amino-6-[2-(cyclopropylmethoxy)-6-hydroxyphenyl]-4-(4-piperidinyl)-3-pyridinecarbonitrile; | ||
SMILES | C1CC1COC2=CC=CC(=C2C3=NC(=C(C(=C3)C4CCNCC4)C#N)N)O | ||
Chemical Name | |||
Formula | C21H24N4O2 | M. Wt | 364.44 |
Purity | 98% | Storage | Store at 4-8°C |
Description | ACHP is an IκB kinase inhibitor that inhibits DNA binding activity of NF-κB, blocks NF-κB pathway in multiple myeloma cell lines, and induces cell growth arrest and apoptosis. It also inhibits STAT3 signaling in NSCLC in vitro. |
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