Vanoxerine dihydrochloride
Data Sheet
For research use only. Not for human use.
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| CAS No. | 67469-78-7 | Cat. No. | BCP02306 |
| Name | Vanoxerine dihydrochloride | ||
| Synonyms | GBR-12909 dihydrochloride; GBR12909 dihydrochloride; GBR 12909 dihydrochloride; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C28H32F2N2O.2(HCl) | M. Wt | 523.49 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | GBR-12909 is a potent dopamine transport blocker studied extensively in rats. By inhibiting DAT function, GBR-12909 was able to induce a bipolar disorder mania-like phenotypes in mice. Also shown to cause postnatal changes to produce useful ADHD animal models. GBR-12909 caused an increase in core body temperature when administered to serotonin transporter knockout mice. Reportedly mimics cocaine-mediated enhancement of Tat neurotoxicity in rat midbrain primary cell cultures. | ||
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