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SB-334867 Chemical Structure

SB-334867

Data Sheet For research use only. Not for human use.
Cat. No. :BCP28004CAS No. :792173-99-0Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 792173-99-0 Cat. No. BCP28004
Name SB-334867
Synonyms SB 334867; SB334867;SB-334867A;SB 334867A;SB334867A;
SMILES O=C(NC1=CC(OC(C)=N2)=C2C=C1)NC3=CC=NC4=CC=CN=C43
Chemical Name
Formula C17H13N5O2 M. Wt 319.32
Purity 98% Storage Store at 4-8°C
Description SB-334867 is an orexin antagonist. It was the first non-peptide antagonist developed that is selective for the orexin receptor subtype OX1, with around 50x selectivity for OX1 over OX2 receptors. It has been shown to produce sedative and anorectic effects in animals, and has been useful in characterising the orexinergic regulation of brain systems involved with appetite and sleep, as well as other physiological processes. Orexin antagonists have multiple potential clinical applications including the treatment of drug addiction, insomnia, obesity and diabetes.
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