EMPA
Data Sheet
For research use only. Not for human use.
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| CAS No. | 680590-49-2 | Cat. No. | BCP23952 |
| Name | EMPA | ||
| Synonyms | 7MA; | ||
| SMILES | CCN(CC1=CN=CC=C1)C(=O)CN(C2=CN=C(C=C2)OC)S(=O)(=O)C3=CC=CC=C3C | ||
| Chemical Name | |||
| Formula | C23H26N4O4S | M. Wt | 454.54 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | EMPA is a highly potent, selective OX2 receptor antagonist (IC50 values are 2.3 nM and 1900 nM for OX2 and OX1 respectively). Displays negligible or no inhibition of a panel of 80 receptors. Blocks orexin-B- and orexin-A-invoked calcium mobilization in hOX2-expressing CHO cells (IC50 values are 7.9 nM and 8.8 nM respectively); reverses orexin-B-induced hyperlocomotion in mice. Brain penetrant. | ||
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