Moexipril hydrochloride New
Data Sheet
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| CAS No. | 82586-52-5 | Cat. No. | BCP21379 |
| Name | Moexipril hydrochloride | ||
| Synonyms | Moexipril HCL; RS 10085; RS-10085; RS10085; SPM-925; SPM 925; SPM925; CI-925; CI 925; CI925; | ||
| SMILES | CCOC(=O)C(CCC1=CC=CC=C1)NC(C)C(=O)N2CC3=CC(=C(C=C3CC2C(=O)O)OC)OC.Cl | ||
| Chemical Name | |||
| Formula | C27H35ClN2O7 | M. Wt | 535.03 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Moexipril Hydrochloride is the hydrochloride salt form of moexipril, a prodrug and non-sulfhydryl angiotensin converting enzyme (ACE) inhibitor with antihypertensive activity. Moexipril hydrochloride is hydrolized into its active form moexiprilat, which competitively inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the actions of the potent vasoconstrictor angiotensin II and leads to vasodilatation. It also prevents angiotensin II-induced aldosterone secretion by the adrenal cortex, thereby promoting diuresis and natriuresis. Moexipril hydrochloride also directly suppresses renin release. | ||
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