Benazepril HCl New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 86541-74-4 | Cat. No. | BCP27638 |
| Name | Benazepril HCl | ||
| Synonyms | Benazepril hydrochloride;Lotension;CGS 14824A HCl;CGS-14824A;CGS14824A; | ||
| SMILES | CCOC(=O)C(CCC1=CC=CC=C1)NC2CCC3=CC=CC=C3N(C2=O)CC(=O)O.Cl | ||
| Chemical Name | |||
| Formula | C24H28N2O5.HCl | M. Wt | 460.95 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Benazepril Hydrochloride is the hydrochloride salt of benazepril, a carboxyl-containing angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. As a prodrug, benazepril is metabolized to its active form benazeprilat. Benazeprilat competitively binds to and inhibits ACE, thereby blocking the conversion of angiotensin I to angiotensin II. This prevents the potent vasoconstrictive actions of angiotensin II, resulting in vasodilation. Benazeprilat also decreases angiotensin II-induced aldosterone secretion by the adrenal cortex, which leads to an increase in sodium excretion and subsequently increases water outflow. | ||
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