Hexestrol
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CAS No. | 84-16-2 | Cat. No. | BCP03061 |
Name | Hexestrol | ||
Synonyms | Bibenzyl;Cycloestrol;Dihydro-stilbestro;Dihydrostilbestrol;Estra-Plex; | ||
SMILES | |||
Chemical Name | |||
Formula | C18H22O2 | M. Wt | 270.37 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Hexestrol binds to ERα with EC50 of 0.07 nM and to ERβ with EC50 of 0.175 nM. Hexestrol inhibits activity of AKR1B13 with IC50 of 3.2 μM. Hexestrol inhibits the d-galactose dehydrogenase activity of thermophilus aldose 1-dehydrogenase with IC50 of 0.063 mM. Hexestrol inhibits the dehydrogenase activity of AKR1C20 towards 10 μM 4-androsten-3α-o1-17-one with IC50 values of 2.7 μM. Hexestrol inhibits 17HSD5 with IC50 of 30 μM, and inhibits TBER1 with IC50 of 0.8 μM. Hexestrol reacts with DNA through the catechol quinone, thus can be a carcinogen. |
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