KU 60019 New
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 925701-46-8 | Cat. No. | BCP30241 |
| Name | KU 60019 | ||
| Synonyms | KU-60019;KU60019; | ||
| SMILES | CC1CN(CC(O1)C)CC(=O)NC2=CC3=C(C=C2)SC4=C(C=CC=C4C3)C5=CC(=O)C=C(O5)N6CCOCC6 | ||
| Chemical Name | |||
| Formula | C30H33N3O5S | M. Wt | 547.68 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | KU-60019 is a potent and reversible inhibitor of ATM kinase with IC50 of 6.3 nM. It is an improved analogue of KU-55933. It exhibits little to no nonspecific target effects against a panel of 229 protein kinases and displays similar target selectivity to KU 55933. It blocks the phosphorylation of ATM substrate proteins. It sensitizes glioma cells to radiation and also sensitizes the normal fibroblasts but not the A-T fibroblasts to radiation. It inhibits migration and invasion of glioma cells in vitro. | ||
Recommend Products
More >
-
ATM Inhibitor-5
Cat. No.：BCP47340
No.：2020089-41-0
Product Details -
Camonsertib
Cat. No.：BCP46512
No.：2417489-10-0
Product Details -
-
-
Gartisertib
Cat. No.：BCP44100
No.：1613191-99-3
Product Details -
AZD6738 chiral mixtures
Cat. No.：BCP38320
No.：1352280-97-7
Product Details -
(S)-Ceralasertib
Cat. No.：BCP38319
No.：1352226-87-9
Product Details -
-
BAY-1895344 hydrochloride
Cat. No.：BCP31861
No.：BAY-1895344HCl
Product Details -
-
-
-
ATR inhibitor 1
Cat. No.：BCP23596
No.：1613200-51-3
Product Details -
-
-
-
-
-
-
Tags:KU 60019 supplier,KU 60019 purchase,KU 60019 manufacturer,KU 60019 distributor,KU 60019 cost,KU 60019 buy,KU 60019 for sale