AZ20
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1233339-22-4 | Cat. No. | BCP09895 |
| Name | AZ20 | ||
| Synonyms | AZ-20;AZ 20; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C21H24N4O3S | M. Wt | 412.51 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | in vitro: AZ20 decreases pChk1 Ser345, pChk1 Ser317 and pChk1 Ser296 levels in a concentration-dependent manner. Prolonged exposure with AZ20 increases H2AX pan-nuclear staining, indicative of replication stress. in vivo: AZ20 induces significant tumour growth inhibition in vivo at well tolerated doses. | ||
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