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CAS No. | 1041852-85-0 | Cat. No. | BCP36143 |
Name | AZD7507 | ||
Synonyms | AZD-7507; AZD 7507; | ||
SMILES | CC1=CC(=C(C=C1)NC2=C(N=NC3=CC(=C(C=C32)N4CCN(CC4)CCO)OC)C(=O)N)F | ||
Chemical Name | |||
Formula | C23H27FN6O3 | M. Wt | 454.51 |
Purity | 98% | Storage | Store at 4-8°C |
Description | AZD7507 is a potent and selective CSF-1R inhibitor (32 nM cell activity), AZD7507 is considered a promising compound as it retained the desired potency and oral pharmacokinetic properties of AZ683. Moreover, in a telemetry study in dogs given a single oral dose, there was no cardiovascular toxicity, no elevation of troponin related to the treatment, and no alteration in the ECG. |
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