PLX5622 New
Data Sheet
For research use only. Not for human use.
| Size | Price | Stock | Quotation Inquiry |
|---|---|---|---|
| 500.00 mg | Get quote | In-stock | Quotation Inquiry |
| 1.00 g | Get quote | In-stock | Quotation Inquiry |
| 100.00 g | Get quote | In-stock | Quotation Inquiry |
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| CAS No. | 1303420-67-8 | Cat. No. | BCP31350 |
| Name | PLX5622 | ||
| Synonyms | PLX-5622; PLX 5622; | ||
| SMILES | CC1=CN=C2C(C(CC3=C(F)N=C(NCC4=CC(F)=CN=C4OC)C=C3)=CN2)=C1 | ||
| Chemical Name | |||
| Formula | C21H19F2N5O | M. Wt | 395.41 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | PLX5622 is a highly selective brain penetrant and oral active CSF1R inhibitor. PLX5622 has been shown to eliminate microglia from the brain, which can be sustained in wild-type and the Alzheimer's disease model mice (3xTg-AD model). In the AD model PLX5622 prevents microglial association with amyloid β plaques and improves cognition. | ||
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