AC-264613 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 1051487-82-1 | Cat. No. | BCP25509 |
| Name | AC-264613 | ||
| Synonyms | AC 264613; AC264613; | ||
| SMILES | CC(=NNC(=O)C1C(CNC1=O)C2=CC=CC=C2)C3=CC(=CC=C3)Br | ||
| Chemical Name | |||
| Formula | C19H18BrN3O2 | M. Wt | 400.28 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | AC-264613 is the first agonist of the G-protein-coupled receptor (GPCR) protease activated receptor 2 (PAR2). AC-264613 suppresses interferon regulatory factor 5 and decreases interleukin-12p40 production by lipopolysaccharide-stimulated macrophages. AC-264613 activated PAR2 signaling in cellular proliferation assays, phosphatidylinositol hydrolysis assays, and Ca(2+) mobilization assays, with potencies ranging from 30 to 100 nM. | ||
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