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CAS No. | 1065110-43-1 | Cat. No. | BCP45867 |
Name | PF-4479745 | ||
Synonyms | PF-04479745; PF04479745; PF 04479745; PF-4479745; PF4479745; PF 4479745; | ||
SMILES | CC1CNCCC2=C1N=C(N=C2NC)CC3=CC=CC=C3 | ||
Chemical Name | |||
Formula | C17H22N4 | M. Wt | 282.38 |
Purity | 98% | Storage | Store at 4-8°C |
Description | PF-4479745 is a potent and selective 5-HT2C agonist (EC50 = 10 nM). PF-4479745 displayed robust pharmacology in a preclinical canine model of stress urinary incontinence (SUI) and no measurable functional agonism at the key selectivity targets 5-HT2A and 5-HT2B in relevant tissue-based assay systems. |
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