KN-93 Phosphate
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 1188890-41-6 | Cat. No. | BCP16226 |
| Name | KN-93 Phosphate | ||
| Synonyms | KN 93 Phosphate;KN93 Phosphate; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C26H32ClN2O8PS | M. Wt | 599.03 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | KN-93 (phosphate) is a potent and selective inhibitor of Ca2+/calmodulin-dependent kinase II (CaMKII) (Ki = 370 nM), inhibiting both the α- and β-subunits of CaMKII.It does not have significant effects on cAMP-dependent protein kinase, Ca2+/phospholipid-dependent protein kinase, myosin light chain kinase, or Ca2+ phosphodiesterase activity. It inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM).KN-93 can block voltage-gated potassium (Kv) channels when applied extracellularly, independent of its CaMKII action.More recently, KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes, constitutive phosphorylation of 5-lipoxygenase in 3T3 cells, and Ca2+-dependent activation of HIF-1α in colon cancer cells. | ||
Recommend Products
More >
-
Calmidazolium chloride
Cat. No.：BCP46455
No.：57265-65-3
Product Details -
A-3 Hydrochloride
Cat. No.：BCP37347
No.：78957-85-4
Product Details -
-
-
KN92 phosphate
Cat. No.：BCP28997
No.：1135280-28-2
Product Details -
KN-93 hydrochloride
Cat. No.：BCP25921
No.：1956426-56-4
Product Details -
-
STO-609 acetate
Cat. No.：BCP19299
No.：1173022-21-3
Product Details -
CaMKII-IN-1
Cat. No.：BCP19054
No.：1208123-85-6
Product Details -
KN-93 phosphate
Cat. No.：BCP18893
No.：1913269-12-1
Product Details -
-
KN-92 hydrochloride
Cat. No.：BCP10626
No.：1431698-47-3
Product Details -
-
-
-
Cefatrizine
Cat. No.：BCP07924
No.：51627-14-6
Product Details
Tags:KN-93 Phosphate supplier,KN-93 Phosphate purchase,KN-93 Phosphate manufacturer,KN-93 Phosphate distributor,KN-93 Phosphate cost,KN-93 Phosphate buy,KN-93 Phosphate for sale