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CAS No. | 176708-42-2 | Cat. No. | BCP35203 |
Name | KN92 | ||
Synonyms | KN 92;KN-92; | ||
SMILES | CN(CC=CC1=CC=C(C=C1)Cl)CC2=CC=CC=C2NS(=O)(=O)C3=CC=C(C=C3)OC | ||
Chemical Name | |||
Formula | C24H25ClN2O3S | M. Wt | 456.98 |
Purity | 98% | Storage | Store at 4-8°C |
Description | KN-92 is intended to be used as a control compound in studies designed to elucidate the antagonist activities of KN-93. KN-93 inhibits histamine-induced aminopyrine uptake in parietal cells (IC50 = 300 nM). KN-93 has been used to implicate roles for CaMKII in Ca2+-induced Ca2+ release in cardiac myocytes, constitutive phosphorylation of 5-lipoxygenase in 3T3 cells, and Ca2+-dependent activation of HIF-1α in colon cancer cell. |
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