Topotecan HCl
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 119413-54-6 | Cat. No. | BCP00930 |
| Name | Topotecan HCl | ||
| Synonyms | Hycamtin;Nogitecan hydrochlorid;NSC-609699;NSC 609699;NSC609699; | ||
| SMILES | |||
| Chemical Name | |||
| Formula | C23H23N3O5.HCl | M. Wt | 457.91 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | Stronger drug activity of Topotecan is observed for DU-145 Luc and MCF-7 Luc cells.Topotecan causes cytotoxicity during the course of DNA replication by stabilizing the covalent complex between topoisomerase I and DNA and preventing the religation of enzyme-linked single-strand DNA break. Topotecan stabilizes topoisomerase I/DNA cleavable complexes in radiation-resistant human B-lineage acute lymphoblastic leukemia (ALL) cells, causes rapid apoptotic cell death despite high-level expression of bcl-2 protein, and inhibits ALL cell clonogenic growth in a dose-dependent fashion. | ||
Recommend Products
More >
-
-
Irinotecan sucrosofate
Cat. No.：BCP49278
No.：1361317-83-0
Product Details -
Voreloxin Hydrochloride
Cat. No.：BCP49069
No.：175519-16-1
Product Details -
Indimitecan
Cat. No.：BCP46636
No.：915360-05-3
Product Details -
-
Bisantrene dihydrochloride
Cat. No.：BCP46265
No.：71439-68-4
Product Details -
ARN-21934
Cat. No.：BCP44949
No.：2230854-93-8
Product Details -
-
Rebeccamycin
Cat. No.：BCP41470
No.：93908-02-2
Product Details -
Chimmitecan
Cat. No.：BCP40436
No.：185425-25-6
Product Details -
-
Exatecan mesylate dihydrate
Cat. No.：BCP36302
No.：197720-53-9
Product Details -
Phenoxodiol
Cat. No.：BCP34699
No.：81267-65-4
Product Details -
-
-
LMP744 hydrochloride
Cat. No.：BCP34016
No.：308246-57-3
Product Details -
-
-
Levofloxacin hydrochloride
Cat. No.：BCP24629
No.：177325-13-2
Product Details -
Chebulanin
Cat. No.：BCP28487
No.：166833-80-3
Product Details
Tags:Topotecan HCl supplier,Topotecan HCl purchase,Topotecan HCl manufacturer,Topotecan HCl distributor,Topotecan HCl cost,Topotecan HCl buy,Topotecan HCl for sale