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CAS No. | 1198780-43-6 | Cat. No. | BCP39699 |
Name | PRI-724 | ||
Synonyms | PRI 724;PRI724; | ||
SMILES | CC1C2N(C(C(=O)N1CC3=CC=CC4=C3N=CC=C4)CC5=CC=C(C=C5)O)C(=O)CN(N2C(=O)NCC6=CC=CC=C6)C | ||
Chemical Name | |||
Formula | C33H35N6O7P | M. Wt | 578.66 |
Purity | 98% | Storage | Store at 4-8°C |
Description | PRI-724 is the second-generation, potent and specific inhibitor of CBP/β-Catenin complex, and a modulator of the β-Catenin dependent canonical Wnt signaling pathway in cancer stem cells. PRI-724 is a pro-drug, from which the active form C-82 (our Prod No. CT-C82) is generated in vivo rapidly. PRI-724 is currently being evaluated as therapies in oncology and fibrosis indications (refs 1, 2). |
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