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CAS No. | 173436-66-3 | Cat. No. | BCP35746 |
Name | MSAB | ||
Synonyms | Methyl 3-(4-methylbenzenesulfonamido)benzoate; | ||
SMILES | CC1=CC=C(C=C1)S(=O)(=O)NC2=CC=CC(=C2)C(=O)OC | ||
Chemical Name | |||
Formula | C15H15NO4S | M. Wt | 305.35 |
Purity | 98% | Storage | Store at 4-8°C |
Description | MSAB is a selective inhibitor of Wnt/β-catenin signaling. MSAB shows potent anti-tumor effects selectively on Wnt-dependent cancer cells in vitro and in mouse cancer models. MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes. |
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