IWP-O1 New
Data Sheet
For research use only. Not for human use.
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| CAS No. | 2074607-48-8 | Cat. No. | BCP41115 |
| Name | IWP-O1 | ||
| Synonyms | IWPO1; IWP O1; | ||
| SMILES | C1=CC=C(C=C1)C2=CN=C(C=C2)NC(=O)CN3C(=C(N=N3)C4=CC=NC=C4)C5=CC=CC=C5 | ||
| Chemical Name | |||
| Formula | C26H20N6O | M. Wt | 432.48 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | IWP-O1 is highly potent Porcn inhibitor, The acyltransferase Porcupine (Porcn) is essential for the secretion of Wnt proteins which contribute to embryonic development, tissue regeneration, and tumorigenesis. IWP-O1 has an EC50 value of 80pM in a cultured cell reporter assay of Wnt signaling. Additionally, IWP-O1 has significantly improved metabolic stability over our previously reported Porcn inhibitors. | ||
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