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CAS No. | 1200493-78-2 | Cat. No. | BCP25878 |
Name | Atabecestat | ||
Synonyms | JNJ-54861911; JNJ54861911; JNJ 54861911; RSC-385896; RSC 385896; RSC385896; | ||
SMILES | CC1(C=CSC(=N1)N)C2=C(C=CC(=C2)NC(=O)C3=NC=C(C=C3)C#N)F | ||
Chemical Name | |||
Formula | C18H14FN5OS | M. Wt | 367.4 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Atabecestat (JNJ-54861911) is a potent brain-penetrant and orally active β-site amyloid precursor protein cleaving enzyme 1 (BACE1) inhibitor, achieves robust and high CSF Aβ reduction. Atabecestat (JNJ-54861911) is tolerated and displays a sustained pharmacokinetic (PK) and pharmacodynamic (PD) characteristics. Atabecestat (JNJ-54861911) has the potential for Alzheimer's Disease treatment. |
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