Home   >  
GPCR/G Protein
  • Wnt/Stem Cell
∨
  >  
PKA
  >   H-89
H-89 Chemical Structure

H-89

Data Sheet For research use only. Not for human use.
Cat. No. ：BCP02706CAS No. ：127243-85-0Purity：98%
chem_1Get Quotation Now
 Tel: 0086-17754423994   or   orders@biochempartner.com
Real-Time Inquiry ×

* Required Fields.

Please complete the form below and you will get the price list in 1 minute.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
Inquiry Online ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
Bulk Inquiry ×

* Required Fields.

Please complete the form below and we will contact you shortly.

Product name

  

* Applicant name

Catalog Number

  

* Institution/Company

* Email address

  

Phone number

Country

  

* Quantity Required

Remarks
Submit
  • Chemical Properties&Biological Activity
CAS No. 127243-85-0 Cat. No. BCP02706
Name H-89
Synonyms H 89;H89;H-89 2HCl;H-89 DIHYDROCHLORIDE;
SMILES
Chemical Name
Formula C20H20BrN3O2S M. Wt 446.36
Purity 98% Storage Store at 4-8°C
Description H89 2HCl is a potent PKA (cAMP-dependent) protein kinase A inhibitor with Ki of 48 nM, exhibits 10-fold selectivity over PKG, exhibits >500-fold selectivity over PKC, MLCK, calmodulin kinase II and casein kinase I/II. Pretreatment of the cells with H-89 (30 μM) 1 h before the addition of forskolin markedly inhibits the forskolin-induced protein phosphorylation in a dose-dependent manner.H89 also inhibits several other kinases with IC50 of 80, 120, 135, 270, 2600 and 2800 nM for S6K1, MSK1, PKA, ROCKII, PKBα and MAPKAP-K1b, respectively. H89 also has activity at some cellular receptors and ion channels, including Kv1.3 K+ channels,β1AR and β2AR.
  • Quality Control&Technical Support
In the process of purchasing and using Biochempartner products, you can consult us if you have any problems: orders@biochempartner.com. We will try our best to solve all your doubts.

Recommend Products

More >

Tags:H-89 supplier,H-89 purchase,H-89 manufacturer,H-89 distributor,H-89 cost,H-89 buy,H-89 for sale

0086-13720134139