(R)-CR8 trihydrochloride New
Data Sheet
For research use only. Not for human use.
Get Quotation Now* Required Fields.
Please complete the form below and you will get the price list in 1 minute.
* Required Fields.
Please complete the form below and we will contact you shortly.
* Required Fields.
Please complete the form below and we will contact you shortly.
| CAS No. | 1786438-30-9 | Cat. No. | BCP45442 |
| Related Products | 294646-77-8（(R)-CR8） | ||
| Name | (R)-CR8 trihydrochloride | ||
| Synonyms | CR8, (R)-Isomer trihydrochloride;(R)-CR8 triHCl;(R)-CR8 3HCl; | ||
| SMILES | CCC(CO)NC1=NC(=C2C(=N1)N(C=N2)C(C)C)NCC3=CC=C(C=C3)C4=CC=CC=N4.Cl.Cl.Cl | ||
| Chemical Name | |||
| Formula | C24H32Cl3N7O | M. Wt | 540.92 |
| Purity | 98% | Storage | Store at 4-8°C |
| Description | (R)-CR8 (CR8) trihydrochloride, a second-generation analog of Roscovitine, is a potent CDK1/2/5/7/9 inhibitor. (R)-CR8 trihydrochloride inhibits CDK1/cyclin B (IC50=0.09 μM), CDK2/cyclin A (0.072 μM), CDK2/cyclin E (0.041 μM), CDK5/p25 (0.11 μM), CDK7/cyclin H (1.1 μM), CDK9/cyclin T (0.18 μM) and CK1δ/ε (0.4 μM). (R)-CR8 trihydrochloride induces apoptosis and has neuroprotective effect. (R)-CR8 trihydrochloride acts as a molecular glue degrader that depletes cyclin K. | ||
Recommend Products
More >
-
-
Inixaciclib
Cat. No.：BCP49218
No.：2370913-42-9
Product Details -
FMF-04-159-2
Cat. No.：BCP48874
No.：2364489-81-4
Product Details -
-
GSK-3/CDK5/CDK2-IN-1
Cat. No.：BCP48519
No.：395074-72-3
Product Details -
LY3143921 hydrate
Cat. No.：BCP48020
No.：1627696-53-0
Product Details -
LY3143921
Cat. No.：BCP48019
No.：1627696-52-9
Product Details -
-
Cdk2/9 Inhibitor
Cat. No.：BCP46934
No.：507487-89-0
Product Details -
Aminopurvalanol A
Cat. No.：BCP46783
No.：220792-57-4
Product Details -
-
-
-
CDK12-IN-2
Cat. No.：BCP46385
No.：2244987-03-7
Product Details -
CDK4/6-IN-6
Cat. No.：BCP46270
No.：2380321-51-5
Product Details -
CDK5-IN-3
Cat. No.：BCP46220
No.：2639542-32-6
Product Details -
KB-0742 hydrochloride
Cat. No.：BCP36919
No.：2416874-75-2
Product Details -
(-)-BAY-1251152
Cat. No.：BCP33291
No.：1610358-59-2
Product Details -
Fascaplysin
Cat. No.：BCP24646
No.：114719-57-2
Product Details -
Aloisine A
Cat. No.：BCP26893
No.：496864-16-5
Product Details
Tags:(R)-CR8 trihydrochloride supplier,(R)-CR8 trihydrochloride purchase,(R)-CR8 trihydrochloride manufacturer,(R)-CR8 trihydrochloride distributor,(R)-CR8 trihydrochloride cost,(R)-CR8 trihydrochloride buy,(R)-CR8 trihydrochloride for sale