Src Kinase Inhibitor I New
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CAS No. | 179248-59-0 | Cat. No. | BCP24909 |
Name | Src Kinase Inhibitor I | ||
Synonyms | Src I1; Src I-1; SrcI1; | ||
SMILES | COC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=C(C=C3)OC4=CC=CC=C4)OC | ||
Chemical Name | |||
Formula | C22H19N3O3 | M. Wt | 373.4 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Src Inhibitor-1 is a member of the class of quinazolines that is quinazoline which is substituted at position 4 by a p-phenoxyanilino group and at positions 6 and 7 by methoxy groups. It is a potent, competitive dual site (both the ATP- and peptide-binding) Src kinase inhibitor. Src Inhibitor-1 is one of the 'gold standards' for Src kinase inhibition that has been shown to use PP1 or PP2 in parallel with Src-I1 to inhbit Src family kinases. It has a role as an EC 2.7.10.2 (non-specific protein-tyrosine kinase) inhibitor. It is a member of quinazolines, a secondary amino compound, an aromatic ether and a polyether. |
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