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TG 100572 Hydrochloride Chemical Structure

TG 100572 Hydrochloride

Data Sheet For research use only. Not for human use.
Cat. No. :BCP21364CAS No. :867331-64-4Purity:98%
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  • Chemical Properties&Biological Activity
CAS No. 867331-64-4 Cat. No. BCP21364
Name TG 100572 Hydrochloride
Synonyms TG-100572; TG 100572; TG100572; TG-100572 HCl;
SMILES CC1=CC(=CC2=C1N=C(N=N2)NC3=CC=C(C=C3)OCCN4CCCC4)C5=C(C=CC(=C5)O)Cl.Cl
Chemical Name
Formula C26H27Cl2N5O2 M. Wt 512.43
Purity 98% Storage Store at 4-8°C
Description TG-100572 is a potent and selective VEGFR2/Src kinase inhibitor. TG100572 inhibits Src kinases and selected receptor tyrosine kinases, induced apoptosis of proliferating endothelial cells in vitro. TG100572 inhibits downstream molecules involved in the vascular endothelial growth factor (VEGF) signaling pathway resulted in markedly diminished levels of HSV-induced angiogenesis and significantly reduced the severity of SK lesions.
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