Chebulinic acid
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CAS No. | 18942-26-2 | Cat. No. | BCP09990 |
Name | Chebulinic acid | ||
Synonyms | NSC69862;NSC-69862;NSC 69862;Eutannin; | ||
SMILES | C1=C(C=C(C(=C1O)O)O)C(=O)OCC2C3C(C(C(O2)OC(=O)C4=CC(=C(C(=C4)O)O)O)OC(=O)C5=CC(=C(C6=C5C(C(C(=O)O3)CC(=O)O)C(C(=O)O6)O)O)O)OC(=O)C7=CC(=C(C(=C7)O)O)O | ||
Chemical Name | |||
Formula | C41H32O27 | M. Wt | 956.68 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Chebulinic Acid is a potent protectant against glutamate-induced neuronal cell death. It has been shown to significantly reduce intracellular reactive oxygen species (ROS) production and Ca2+ influx induced by glutamate, decrease the phosphorylation of mitogen-activated protein kinases (MAPKs), including ERK1/2, JNK, and p38, as well as inhibit pro-apoptotic Bax and increase anti-apoptotic Bcl-2 protein expression. |
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