Pirfenidone New
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CAS No. | 53179-13-8 | Cat. No. | BCP04473 |
Name | Pirfenidone | ||
Synonyms | AMR69; AMR-69; AMR 69; | ||
SMILES | CC1=CN(C(=O)C=C1)C2=CC=CC=C2 | ||
Chemical Name | |||
Formula | C12H11NO | M. Wt | 185.22 |
Purity | 98% | Storage | Store at 4-8°C |
Description | Pirfenidone is an anti-fibrotic drug for the treatment of idiopathic pulmonary fibrosis (IPF). It works by reducing lung fibrosis through downregulation of the production of growth factors and procollagens I and II. Pirfenidone has well-established antifibrotic and anti-inflammatory properties in various in vitro systems and animal models of fibrosis. A number of cell-based studies have shown that pirfenidone reduces fibroblast proliferation, inhibits TGF-β stimulated collagen production and reduces the production of fibrogenic mediators such as TGF-β. |
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